Background: Little is known about the prevalence of cerebral microangiopathy (CM). which is related to cognitive impairment. in an asymptomatic population. Pulsatility index (PI) is an easily measurable parameter of cerebral vascular resistance in transcranial duplex of the middle cerebral artery (MCA) study. https://www.chiggate.com/aptamil-allerpro-syneo-2-900g-online-now/