A focused series of substituted 4H-1. 2. 6-thiadiazin-4-ones was designed and synthesized to probe the anti-cancer properties of this scaffold. Insights from previous kinase inhibitor programs were used to carefully select several different substitution patterns. https://www.markbroyard.com/amazing-price-color-touch-7-97-medium-blonde-cendre-brown-online-now-mega-choice/