In order to obtain topical and non-irritating anti-glaucoma drugs. novel semicarbazide-containing sulfonamide derivatives were designed and synthetized by sugar tail method in this study. The hydrophilic monosaccharides were expected to form interaction with the hydrophilic site of hCA II meanwhile the linker semicarbazides are used to further enhance water solubility. and more import... https://www.bekindtopets.com/deal-alert-NHL-Winnipeg-Jets-Distressed-iPhone-13-Pro-Max-MagSafe-Case-p96268-great-save/