Streptococcus pneumoniae is an opportunistic human bacterial pathogen that usually colonizes the upper respiratory tract. but the invasion and survival mechanism in respiratory epithelial cells remains elusive. Previously. we described that acidic stress-induced lysis (ASIL) and intracellular survival are controlled by ComE through a yet unknown activation mechanism under acidic condi... https://fitnessgravesyardes.shop/product-category/circuit-breaker/