Abstract Objectives Leflunomide (LEF) is a conventional synthetic disease-modifying antirheumatic drug and suppresses T-cell proliferation and activity by inhibiting pyrimidine synthesis using dihydroorotase dehydrogenase (DHODH); however. several studies have demonstrated that LEF possesses anticancer and antiangiogenic effects in some malignant tumors. Therefore. we investigated the... https://www.vwbag.com/product-category/womens-footwear/